Which preexisting condition has been shown to go into remission in up to 62% of patients 6 years after Roux-en-Y gastric bypass?

Which preexisting condition has been shown to go into remission in up to 62% of patients 6 years after Roux-en-Y gastric bypass?

• A. Hypertension
• B. Diabetes
• C. Obesity
• D. Obstructive Sleep Apnea

Answer: (B)

Roux-en-Y gastric bypass often restores normal glucose metabolism in people with type 2 diabetes, not just by weight loss but through rapid hormonal changes that improve how the body handles insulin. After surgery, the gut produces more incretin hormones like GLP-1 and GIP, there’s a drop in ghrelin, and the overall effect is better beta-cell function and lower hepatic glucose production. These changes can improve blood sugar very quickly—often allowing reduction or cessation of diabetes medications—while continued weight loss sustains improved insulin sensitivity over time. That combination leads to a relatively high chance of long-term diabetes remission, and the figure described (around 60% at six years) reflects that sustained effect seen in many long-term studies. Hypertension and obstructive sleep apnea frequently improve after surgery, but they don’t remit as consistently as diabetes, and obesity is the condition being treated rather than something that typically goes into remission in the same sense. So the preexisting condition most likely to go into remission years after Roux-en-Y is type 2 diabetes.

Roux-en-Y gastric bypass often restores normal glucose metabolism in people with type 2 diabetes, not just by weight loss but through rapid hormonal changes that improve how the body handles insulin. After surgery, the gut produces more incretin hormones like GLP-1 and GIP, there’s a drop in ghrelin, and the overall effect is better beta-cell function and lower hepatic glucose production. These changes can improve blood sugar very quickly—often allowing reduction or cessation of diabetes medications—while continued weight loss sustains improved insulin sensitivity over time. That combination leads to a relatively high chance of long-term diabetes remission, and the figure described (around 60% at six years) reflects that sustained effect seen in many long-term studies. Hypertension and obstructive sleep apnea frequently improve after surgery, but they don’t remit as consistently as diabetes, and obesity is the condition being treated rather than something that typically goes into remission in the same sense. So the preexisting condition most likely to go into remission years after Roux-en-Y is type 2 diabetes.